DOI:
https://doi.org/10.7759/cureus.105875
Cite:
Sahu S, Sen S, Das M, et al. (March 26, 2026) Assessment of Retinal Nerve Fiber Layer Changes in Patients With Chronic Kidney Disease: A Cross-Sectional Study. Cureus 18(3): e105875. doi:10.7759/cureus.105875
Notes:
- In patients with chronic kidney disease, both the retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) are significantly thinner than in healthy individuals, indicating that neurodegeneration can progress even when intraocular pressure is normal.
- Greater impairment of renal function (lower eGFR) is associated with more severe retinal structural damage, suggesting a correlation with CKD severity.
- Optical coherence tomography (OCT) may serve as a useful non-invasive biomarker for detecting systemic microvascular and neurodegenerative changes in CKD.
#ChronicKidneyDisease #RNFL #OphthalmicExamination
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